In the period 1996 – 1998 MCMB introduced, together with the Institute of Oncology, molecular genetic analysis of B cell lymphoma / synovial sarcoma. This was the start of molecular genetic analysis in Slovenian oncology.
Supportive research projects:
- Interinstitutional national research program P1-0104 Functional Genomics and Biotechnology for Health (R. Komel); 1999-2004.
- J1―8762 Molecular biology and genetics in biomedical research; national basic research project, R. Komel, 1/1/1997―31/12/1999.
Clinical partner:
- Institute of Oncology, Department of Pathology (Prof. Rastko Golouh, M.D.; Dr. Janez Jančar, M.D.).
Clinical translation:
After completed M.Sc. education in our laboratory Ira Koković moved in 1997/98 to the Institute of Oncology where MCMB assisted in starting the independent molecular diagnostic laboratory (molecular oncology), under suppervision of Prof. Rastko Golouh.
Researchers involved:
| Researcher | Position |
| Radovan Komel | Head of Department / Project supervisor |
| Ira Koković (Todorović) | M.Sc. & Ph.D. student |
Education:
| Student | Thesis | Title | Year | Supervisors |
| Ira Koković | PhD | Predictive value of SYT-SSX chimeric transcripts from paraffin embedded samples of synovial sarcoma. | 2005 | Radovan Komel
Rastko Golouh |
| Ira Koković | MSc | Introduction of molecular biology methods in diagnostics of lymphomas. | 1997 | Radovan Komel
Vladimir Kotnik |
Selected publications
- Koković I. et al. (2004): Are there geographical differences in the frequency of SYT-SSX1 and SYT-SSX2 chimeric transcripts in synovial sarcoma?. Cancer Detection and Prevention 28(4): 294-301.
- Koković I. et al. (1998): Determination of clonality of lymphoid proliferations using the polymerase chain reaction (Določanje klonskosti limfoidnih proliferacij s pomočjo reakcije verižne polimerizacije). Zdravniški Vestnik 67(2): 83-87.
- Koković I. et al. (1996): Detection of immunoglobulin gene rearrangement of B cell lymphoma in formalin-fixed, paraffin-embedded tissues by polymerase chain reaction. Croatian – Slovenian Meeting »Molecular Oncology Today«. Proceedings of the Croatian – Slovenian Meeting, Zagreb (Croatian Ligue Against Cancer; M. Osmak, J. Škrk, eds.), 1996, pp. 155-157.
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